Mercedes-Benz GLS-Class MPG by Year

By , Gas Mileage Calculators

Here's the official EPA Mercedes-Benz GLS-Class MPG for every engine and drivetrain from 2017 to 2027.

Best 2026 GLS-Class
21 MPG
2026 GLS450 4matic (AWD)
Most efficient GLS-Class ever
21 MPG
2024-2027 GLS450 4matic
2026 range
15-21 MPG
Across 4 versions rated that year

GLS-Class MPG by Year and Version

4 configurations

The EPA has rated 36 configurations of the GLS-Class. Pick a year to compare engines and drivetrains.

EPA ratings for the 2026 Mercedes-Benz GLS-Class
VersionEngineTransmissionDriveCityHwyCombinedEPA
GLS450 4maticMild hybridPremium Gasoline3.0L 6-cylAuto 9-spdAWD192421View
AMG GLS63 4matic PlusMild hybridPremium Gasoline4.0L 8-cylAuto 9-spdAWD152017View
GLS580 4maticMild hybridPremium Gasoline4.0L 8-cylAuto 9-spdAWD142016View
GLS600 4matic MaybachMild hybridPremium Gasoline4.0L 8-cylAuto 9-spdAWD131815View

GLS-Class MPG Over the Years

Each bar shows the range of combined MPG across every GLS-Class configuration the EPA rated that year, from the thirstiest version to the most efficient. Hover or tap a year to see the numbers.

Mercedes-Benz GLS-Class combined MPG range by model year
Gas engines only

Years When GLS-Class Fuel Economy Changed

Most years look a lot like the one before. These are the years where the EPA numbers moved in a way that matters if you're shopping for a used GLS-Class.

How the GLS-Class Compares

The EPA rated 55 full-size SUVs for 2026. The best GLS-Class version, at 21 MPG combined, ties for 28th with 5 other models of 55. Combined ratings in the class run from 14 to 37 MPG, with a median of 21. Plug-in hybrids and electric models are ranked separately.

Best combined rating for each full-size SUV the EPA rated for 2026, top 5, plus the GLS-Class
RankModelCombined
1Jeep Cherokee37 MPG
2Toyota Grand Highlander36 MPG
3Toyota Highlander35 MPG
4Hyundai Palisade34 MPG
5Lexus TX27 MPG
28Mercedes-Benz GLS-Class21 MPG

What Does a GLS-Class Cost to Fuel?

Pick a GLS-Class, then enter your gas price and how much you drive. The math uses the EPA city and highway ratings, weighted by how much of your driving happens in each.

Yearly cost
Enter a price
Per month-
Gallons per year-
Cost per mile-
Your blended MPG-
Real-world results vary with driving style, weather, tire condition and maintenance.

GLS-Class MPG Questions

Which GLS-Class year gets the best gas mileage?

The 2024 to 2027 GLS450 4matic holds the top EPA rating at 21 MPG combined (19 city, 24 highway).

Why doesn't my GLS-Class match the EPA numbers?

EPA ratings come from standardized lab tests. Your results depend on speed, climate, idling, passengers and cargo, roof racks, tire pressure and upkeep. The ratings are best for comparing one vehicle against another. To track your own numbers, try the MPG calculator.

Keep Going

Compare two vehiclesSee the yearly fuel cost gap between a GLS-Class and another vehicle. Price a road tripWork out the fuel cost for a trip in your GLS-Class on our sister site, FuelPriceCalculator.com. All Mercedes-Benz modelsRatings for the E-Class, C-Class, S-Class, SL-Class and every other Mercedes-Benz. Mercedes-Benz G-Class MPGAnother Mercedes-Benz, rated 15 to 18 MPG combined for 2026. Mercedes-Benz GLE-Class MPGAnother Mercedes-Benz, rated 17 to 23 MPG combined for 2026. Chevrolet Suburban MPGA full-size SUV from Chevrolet, rated 16 to 23 MPG combined for 2026. Toyota 4Runner MPGA full-size SUV from Toyota, rated 21 to 23 MPG combined for 2026. Land Rover Range Rover MPGA full-size SUV from Land Rover, rated 18 to 23 MPG combined for 2026.

Where These Numbers Come From

Every figure on this page comes from the U.S. EPA fuel economy dataset on fueleconomy.gov, pulled together by Cedrick Reese. The file lists 36 ratings for the Mercedes-Benz GLS-Class from 2017 to 2027. Each row in the table links to the matching EPA vehicle record, so you can check any figure against the source. When the EPA posts an updated file with new model years or corrected ratings, this page is rebuilt from it. The cost calculator uses the gas price you enter rather than a national average, so the result fits where you live.

Ratings on this page come from the EPA file downloaded on October 1, 2026.

Sources